Details for gene set NCI_IL12-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_IL12-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.6244097
Normalized Enrichment Score (NES)	-1.6039304
Nominal p-value	0.0016638935
FDR q-value	0.11027821
FWER p-Value	0.721

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IL12RB1	2230338 5420053	494	2.962	-0.0032	No
2	STAT5A	2680458	905	2.165	-0.0082	No
3	IL12RB2	6020465	1184	1.832	-0.0088	No
4	TYK2	1660465 1740736	1410	1.615	-0.0081	No
5	BCL3	3990440	1455	1.580	0.0020	No
6	TBX21	5270594	1575	1.458	0.0071	No
7	TGFB1	1940162	1841	1.237	0.0026	No
8	CD8B	1940411 2570035	2275	0.967	-0.0131	No
9	UBE2D3	3190452	2294	0.950	-0.0066	No
10	NFKB1	5420358	2322	0.926	-0.0007	No
11	STAT6	1190010 5720019	2499	0.821	-0.0037	No
12	GADD45G	2510142	2603	0.758	-0.0033	No
13	CYLD	6590079	2761	0.674	-0.0064	No
14	CCL3	2810092	2794	0.662	-0.0029	No
15	CD80	870112	2822	0.650	0.0008	No
16	IL2RA	6620450	2842	0.642	0.0048	No
17	STAT4	1660373 3130019	2935	0.599	0.0046	No
18	RAB7A	450433 4070112 4480324	3030	0.561	0.0040	No
19	TNF	6650603	3118	0.530	0.0035	No
20	IL12A	7100551	3220	0.492	0.0019	No
21	CCL4	50368 430047	3297	0.460	0.0014	No
22	IL27RA	940093	3499	0.394	-0.0063	No
23	MALT1	4670292	3693	0.324	-0.0142	No
24	PRKCA	6400551	3738	0.311	-0.0141	No
25	REL	360707	3934	0.268	-0.0225	No
26	JAK2	3780528 6100692 6550577	3956	0.262	-0.0215	No
27	IL1B	2640364	4401	0.191	-0.0440	No
28	BIRC2	2940435 4730020	4414	0.189	-0.0431	No
29	IL1R1	3850377 6180128	4705	0.157	-0.0576	No
30	IL13	7040021	5273	0.114	-0.0873	No
31	RIPK2	5050072 6290632	5335	0.111	-0.0897	No
32	IL4	6020537	5544	0.100	-0.1002	No
33	IL12B	460008	5992	0.079	-0.1237	No
34	ATM	3610110 4050524	6074	0.076	-0.1274	No
35	GZMA	3390315	6432	0.063	-0.1462	No
36	PIAS2	1690301 5900647	7107	0.045	-0.1823	No
37	PIK3R1	4730671	7165	0.043	-0.1850	No
38	RAN	2260446 4590647	7457	0.038	-0.2004	No
39	XPO1	540707	8282	0.022	-0.2448	No
40	ARRB2	2060441	9730	-0.001	-0.3229	No
41	PIK3CA	6220129	9883	-0.003	-0.3311	No
42	IL6	380133	10184	-0.007	-0.3473	No
43	CCR5	1980072 5910722	10373	-0.010	-0.3573	No
44	IL27	1990324	10990	-0.020	-0.3905	No
45	SRC	580132	11142	-0.022	-0.3984	No
46	NOD2	2510050	11446	-0.027	-0.4146	No
47	GZMB	380066	11647	-0.031	-0.4252	No
48	IL2	1770725	11676	-0.032	-0.4264	No
49	B2M	5080332 5130059	11787	-0.034	-0.4321	No
50	CHUK	7050736	11886	-0.036	-0.4371	No
51	FBXW11	6450632	11951	-0.037	-0.4403	No
52	IL18	6180039	12002	-0.038	-0.4427	No
53	IL18RAP	3850088	12283	-0.045	-0.4574	No
54	IFNG	5670592	13106	-0.070	-0.5013	No
55	SYK	6940133	13785	-0.106	-0.5371	No
56	IL17A	4280369	14313	-0.150	-0.5643	No
57	FRAP1	2850037 6660010	14493	-0.168	-0.5727	No
58	ETV5	110017	14518	-0.170	-0.5726	No
59	JUN	840170	14564	-0.175	-0.5737	No
60	MAP2K3	5570193	14571	-0.175	-0.5726	No
61	ERC1	1580170 2630717 6110762 6840280	14877	-0.230	-0.5873	No
62	FOS	1850315	15011	-0.260	-0.5924	No
63	IRF1	2340152 3450592 6290121 6980577	15180	-0.299	-0.5991	No
64	FASLG	2810044	15237	-0.321	-0.5996	No
65	CREBBP	5690035 7040050	15330	-0.349	-0.6018	No
66	PRF1	6660309	15336	-0.350	-0.5993	No
67	IKBKG	3450092 3840377 6590592	15419	-0.375	-0.6008	No
68	IKBKB	6840072	15462	-0.391	-0.5999	No
69	IL18R1	270546	15684	-0.491	-0.6080	No
70	CD86	3390471 6200280	15804	-0.543	-0.6101	No
71	ATF2	2260348 2480441	15822	-0.552	-0.6067	No
72	EOMES	2100707	15978	-0.643	-0.6099	No
73	EBI3	5340300	16138	-0.733	-0.6127	No
74	MAPK8	2640195	16187	-0.761	-0.6093	No
75	JAK1	5910746	16259	-0.809	-0.6067	No
76	SPHK2	2030487 4120670 4850114	16532	-0.987	-0.6136	No
77	MAPK9	2060273 3780209 4070397	16570	-1.002	-0.6077	No
78	IL2RB	4730072	16881	-1.233	-0.6146	Yes
79	GADD45B	2350408	16943	-1.289	-0.6077	Yes
80	NFKB2	2320670	17059	-1.421	-0.6027	Yes
81	MAPK14	5290731	17073	-1.446	-0.5920	Yes
82	TRAF6	4810292 6200132	17171	-1.553	-0.5849	Yes
83	RELA	3830075	17220	-1.623	-0.5746	Yes
84	MAP3K14	5890435	17267	-1.682	-0.5638	Yes
85	RELB	1400048	17302	-1.724	-0.5520	Yes
86	LCK	3360142	17665	-2.357	-0.5529	Yes
87	STAT2	3780519	17691	-2.398	-0.5353	Yes
88	GATA3	6130068	17768	-2.566	-0.5190	Yes
89	STAT1	6510204 6590553	17835	-2.706	-0.5012	Yes
90	CD28	1400739 4210093	17840	-2.716	-0.4799	Yes
91	MAP2K6	1230056 2940204	17854	-2.745	-0.4589	Yes
92	IL6ST	5890047	17936	-2.959	-0.4398	Yes
93	CD3D	2810739	17940	-2.964	-0.4165	Yes
94	BCL10	2360397	18036	-3.190	-0.3964	Yes
95	NFKBIA	1570152	18160	-3.680	-0.3739	Yes
96	STAT3	460040 3710341	18169	-3.701	-0.3450	Yes
97	CD4	1090010	18200	-3.836	-0.3163	Yes
98	SOCS1	730139	18267	-4.197	-0.2866	Yes
99	IL2RG	4120273	18336	-4.588	-0.2540	Yes
100	CD3E	3800056	18384	-4.904	-0.2177	Yes
101	CD3G	2680288	18515	-6.372	-0.1743	Yes
102	CD247	3800725 5720136	18546	-6.975	-0.1207	Yes
103	TNFAIP3	2900142	18562	-7.402	-0.0629	Yes
104	TNFRSF1A	1090390 6520735	18584	-8.303	0.0017	Yes